Data Curator - Sequence Families

EBI - European Bioinformatics Institute

Data Curator - Sequence Families

EMBL-EBI - European Bioinformatics Institute

Hinxton, United Kingdom

Organisation data: Service Teams
Job number: EBI01829
Contract Type: Staff Member
Job Function: Technical Officer (gr. 4-6)
Closing date: 12 May 2021

About the team/job

The Sequence Families team, led by Alex Bateman, at the European Bioinformatics Institute (EMBL-EBI) is responsible for a number of world-leading protein family annotation resources, including Pfam and InterPro.

Pfam is a database of protein families, represented by multiple sequence alignments and profile hidden Markov models (HMMs). InterPro is a resource that classifies protein sequences into families, and predicts the presence of functionally important domains and sites. It does this by incorporating protein signatures from 13 different specialist international member databases, including Pfam. We are seeking for a Biocurator to join the team on a full time basis working on the InterPro/Pfam project and contribute to the content of InterPro and Pfam databases.

Your role

Reporting to the Sequence Families Team leader you will be part of the Curation Team that maintains the InterPro and Pfam resources. You will have the opportunity to critically evaluate protein signature models for inclusion in new or existing InterPro entries, as well as writing descriptive abstracts and assigning GO term annotations.

You will also maintain and update Pfam database entries, based on both user contributions and scientific literature and take part in other curation activities, as needed. Some tasks may require the use of command line tools, basic scripts and/or direct querying of relational databases. You will work closely with the rest of the curation and development team to ensure timely updates and releases of the various resources. You will also respond to user queries and requests, as appropriate.

Additionally, you will also help to maintain resource user guides, adding frequently asked questions and updating content where appropriate. Finally, you will have the chance to deliver or assist in the delivery, of in-person and remote training sessions.

Main duties and responsibilities

  • Create and maintain InterPro and Pfam entries through the assessment of protein signature models. This will involve using our curation interfaces and tools (using basic command line);
  • Write descriptive abstracts of protein families and domains, summarizing functional information found within the scientific literature;
  • Augment entries with annotation terms for use in automatic annotation pipelines, for example the use of GO annotations and other data standards;
  • Respond to user and collaborator queries and requests;
  • Use social media to help communicate with the user community;
  • Help develop and deliver training materials, either in person or via the Train Online platform.

You have

  • A degree in a biological or closely related scientific discipline, or equivalent experience in scientific data curation;
  • Several years experience in curating biological data, and/or experimentally investigating proteins;
  • Experience of computational data entry and data standards;
  • Experience in widely used bioinformatics tools related to protein sequence searching and alignment. is essential, using both GUI and command-line;
  • Ability to read, digest and summarize scientific literature;
  • Basic/intermediate Linux/Unix commands;
  • Have excellent communication skills, both written and oral;
  • Attention to detail;
  • Ability to constructively critique database entries and annotations generated by others;
  • Able to manage time and meet deadlines;
  • Good team player.

You might also have

  • A Phd in a biological field would be advantageous but not essential;
  • Experience using HMMER suite to build and search profile HMMs, is highly desirable;
  • Experience developing training materials;
  • Demonstrable experience dealing with database helpdesks;
  • Basic knowledge of querying relational databases, e.g. MySQL;
  • Basic Scripting knowledge;
  • Use of social media for scientific communication.

Why join us

Do something meaningful

At EMBL-EBI you can apply your talent and passion to accelerate science and tackle some of humankind's greatest challenges. EMBL-EBI is a worldwide leader in the storage, analysis and dissemination of large biological datasets. We provide the global research community with access to publicly available databases and tools which are crucial for the advancement of healthcare, food security, and biodiversity.

Join a culture of innovation

We are located on the Wellcome Genome Campus, alongside other prominent research and biotech organisations, and surrounded by beautiful Cambridgeshire countryside. This is a highly collaborative and inclusive community where our employees enjoy a relaxed atmosphere. We are committed to ensuring our employees feel valued, supported and empowered to reach their professional potential.

Enjoy lots of benefits

  • Financial incentives: Monthly family, child and non-resident allowances, annual salary review, pension scheme including 17% employer contribution, death benefit, long-term care, accident-at-work and unemployment insurances;
  • Flexible working arrangements;
  • Private medical insurance for you and your immediate family (including all prescriptions and generous dental & optical cover);
  • Generous time off: 30 days annual leave per year, in addition to eight bank holidays;
  • Relocation package including installation grant (if required);
  • Campus life: Free shuttle bus to and from work, on-site library, subsidised on-site gym and cafeteria, casual dress code, extensive sports and social club activities (on campus and remotely);
  • Family benefits: On-site nursery, 10 days of child sick leave, generous parental leave, holiday clubs on campus and monthly family and child allowances;
  • Benefits for non-UK residents: Visa exemption, education grant for private schooling, financial support to travel back to your home country every second year and a monthly non-resident allowance.

For more details please see our employee benefits page.

What else you need to know

  • Contract duration: This position is a 3 year contract, renewable to a maximum of 9 years;
  • International applicants: We recruit internationally and successful candidates are offered visa exemptions. Read more on our page for international applicants;
  • Diversity and inclusion: At EMBL-EBI, we strongly believe that inclusive and diverse teams benefit from higher levels of innovation and creative thought. We encourage applications from women, LGBTQ+ and individuals from all nationalities;
  • Job location: This role is based in Hinxton, UK and you will be required to relocate once it is safe to do so, if you are currently based abroad. Read more about how we are recruiting during the pandemic;
  • How to apply: To apply please submit a cover letter and a CV through our online system. We aim to provide a response within two weeks after the closing date - 12th May 2021;
  • Interviews: Interviews are likely to be held on Tuesday 1st June 2021.

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Registered address: EuroJobsites Ltd, Unit 8, Kingsmill Business Park, Kingston Upon Thames, London, KT1 3GZ, United Kingdom

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